STNMTZ_19940701_06.tif | George Steinmetz

Adrenocortical dysplasia, achondroplasia, strain: DW/J acel.

Twenty day old siblings with the little one having double recessive trait and the bigger one having it as singly recessive gene. The little one was lucky to live as long as it has. Most die within the first week or two. Clearly this is not a mutation that can be bred using mice that are double recessive as they never live long enough to mate, and are probably sterile anyway. They, like many of these mutants, are created by breeding parents who both carry the desired gene recessively, and thus approximately one quarter of the offspring will have the gene double recessive like the little mutant.

A naturally occurring mutant whose genetics have been studied and are fully reproducible. They are not a product of genetic engineering any more than different breeds of dog or cat. The Jackson lab breeds mice for the traits it wants, and these varieties were discovered as mutants in naturally occurring litters of mice.

The Jackson Laboratory breeds genetically specific mice and ships over two million mice per year to medical research laboratories around the world. This enables scientists in different parts of the world to test and duplicate experiments on genetically identical specimens. The mice are bred for naturally occurring mutations that mimic human maladies. Mice are the best genetic model for medical studies because they are so well known genetically, even better than humans.

Filename: STNMTZ_19940701_06.tif
Copyright: © 1999 George Steinmetz
Image Size: 7213x4846 / 100.0MB; www.georgesteinmetz.com; animal research DNA experiments genetics research Jackson Laboratory scientific lab mouse mice genetic mutations genetic mutant
Contained in galleries: Mouse House

Adrenocortical dysplasia, achondroplasia, strain: DW/J acel. <br />
<br />
Twenty day old siblings with the little one having double recessive trait and the bigger one having it as singly recessive gene. The little one was lucky to live as long as it has. Most die within the first week or two. Clearly this is not a mutation that can be bred using mice that are double recessive as they never live long enough to mate, and are probably sterile anyway. They, like many of these mutants, are created by breeding parents who both carry the desired gene recessively, and thus approximately one quarter of the offspring will have the gene double recessive like the little mutant.<br />
<br />
A naturally occurring mutant whose genetics have been studied and are fully reproducible. They are not a product of genetic engineering any more than different breeds of dog or cat. The Jackson lab breeds mice for the traits it wants, and these varieties were discovered as mutants in naturally occurring litters of mice. <br />
<br />
The Jackson Laboratory breeds genetically specific mice and ships over two million mice per year to medical research laboratories around the world. This enables scientists in different parts of the world to test and duplicate experiments on genetically identical specimens. The mice are bred for naturally occurring mutations that mimic human maladies. Mice are the best genetic model for medical studies because they are so well known genetically, even better than humans.